What condition is considered a non-atherosclerotic vessel disease that primarily affects young smokers?

Buerger's disease is recognized as a non-atherosclerotic vessel disease that predominantly affects young smokers. This condition, also known as thromboangiitis obliterans, is characterized by inflammation and thrombosis of small and medium-sized blood vessels, typically in the arms and legs. The etiology of Buerger's disease is closely linked to tobacco exposure, making smoking a significant risk factor.

Patients with Buerger's disease often present with symptoms such as claudication, rest pain, and ulcers, which arise due to reduced blood flow caused by the inflammation and occlusion of the vessels. The non-atherosclerotic nature of this disease distinguishes it from other conditions like atherosclerosis, which involves plaque buildup in the arteries and is not primarily associated with smoking in young individuals.

In contrast, Raynaud's phenomenon primarily affects blood flow in response to cold or stress rather than being exclusively linked to smoking or young adults. Atherosclerosis is a common vascular condition affecting older populations and is related to multiple risk factors including cholesterol and hypertension, not specifically smoking in the younger demographic. Diabetic angiopathy pertains to vascular complications seen in diabetic patients, unrelated to smoking or age-specific groups.

Understanding these distinctions highlights why Buer